Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FKBP5 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen und Schwein.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
FKBP5
(FK506 Binding Protein 5 (FKBP5))
Andere Bezeichnung
FKBP5
Hintergrund
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alias Symbols: AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10 Protein Interaction Partner: LRRC40, CXorf57, EGLN1, AGO2, CACYBP, CHORDC1, AGO1, KIAA1279, NUDCD3, GLMN, CDC37, SUGT1, PTGES3, NUDC, AHSA1, DNAJB6, AURKB, IKBKG, IRS4, TUBA1A, TTC4, PYGL, PDCD2, CDK11A, HGH1, C14orf80, MCMBP, PNPLA2, ANKMY2, CDC37L1, MCM4, ILK, HSP90AB1, HSP90AA1, H Protein Size: 457